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从免疫功能低下宿主中分离出的白色念珠菌A和B血清型转换表型对伊曲康唑和氟康唑的体外敏感性

In vitro susceptibility to itraconazole and fluconazole of switch phenotypes of Candida albicans serotypes A and B, isolated from immunocompromised hosts.

作者信息

Velegraki A

机构信息

Department of Microbiology, Medical School, University of Athens, Greece.

出版信息

J Med Vet Mycol. 1995 Jan-Feb;33(1):83-5.

PMID:7650586
Abstract

Data from 78 oropharyngeal samples obtained from severely immunocompromised individuals, have shown that the B serotype and the stipple phenotype of Candida albicans isolates have significantly higher minimum inhibitory concentration values towards itraconazole and fluconazole, as compared with the corresponding serotype A phenotype (P < 0.05). The epidemiological significance of the phenotype-dependent drug susceptibility patterns is discussed.

摘要

从严重免疫功能低下个体获取的78份口咽样本数据显示,与相应的A型血清型表型相比,白色念珠菌分离株的B血清型和点彩样表型对伊曲康唑和氟康唑的最低抑菌浓度值显著更高(P < 0.05)。本文讨论了表型依赖性药敏模式的流行病学意义。

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In vitro susceptibility to itraconazole and fluconazole of switch phenotypes of Candida albicans serotypes A and B, isolated from immunocompromised hosts.从免疫功能低下宿主中分离出的白色念珠菌A和B血清型转换表型对伊曲康唑和氟康唑的体外敏感性
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