Warrington R J, Buehler S K, Roberts K B
Experientia. 1976 Jan 15;32(1):110-2. doi: 10.1007/BF01932652.
The supernatants obtained from stimulated tuberculin-sensitive guinea-pig peripheral blood lymphocytes contain factors that induce a cutaneous inflammatory response in normal guinea-pigs similar to the tuberculin reaction and inhibit the migration of normal guinea-pigs peritoneal exudate cells. There appears to be a correlation between the presence of in vitro migration inhibitory activity and inflammatory activity in vivo.
从经刺激的结核菌素敏感豚鼠外周血淋巴细胞获得的上清液中含有一些因子,这些因子能在正常豚鼠中诱导出类似于结核菌素反应的皮肤炎症反应,并抑制正常豚鼠腹腔渗出细胞的迁移。体外迁移抑制活性的存在与体内炎症活性之间似乎存在相关性。