Wrodycki W, Kuydowicz J, Krakowiak M, Michowicz A, Małolepsza E, Białkowska-Warzecha J, Latarska D, Hauk-Szklarek E
Katedry i Kliniki Chorób Zakaźnych AM w Lodzi.
Pol Tyg Lek. 1994;49(20-22):472-4.
81 patients (pts) with bacterial meningitis hospitalised in the Clinic for Infectious Diseases in the years 1990-1991 were treated according to two therapeutic schedules. First: young pts (under 40 years), without coexisting diseases obtained Penicillin G and aminoglycoside and/or synthetic penicillin. Second: pts over 40 years old with coexisting diseases or cases of recurrent meningitis were treated with third-generation cephalosporins and aminoglycoside and/or synthetic penicillin. The mortality was 16% in the study group. 11 of 13 pts with coexisting diseases died. Neurologic sequelae were found in 23% of pts. The complete recovery was obtained in 34% of pts, more often (35.9%) in a group treated with third--generation cephalosporins comparing to 29.4% with other antibiotic therapy.
1990年至1991年间，81例细菌性脑膜炎患者在传染病诊所住院，并按照两种治疗方案进行治疗。第一：年轻患者（40岁以下），无并存疾病，给予青霉素G和氨基糖苷类药物和/或合成青霉素。第二：40岁以上有并存疾病的患者或复发性脑膜炎患者，用第三代头孢菌素和氨基糖苷类药物和/或合成青霉素治疗。研究组的死亡率为16%。13例有并存疾病的患者中有11例死亡。23%的患者出现神经后遗症。34%的患者完全康复，与接受其他抗生素治疗的患者（29.4%）相比，接受第三代头孢菌素治疗的患者更常完全康复（35.9%）。
