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[基于罗兹传染病诊所1990 - 1991年资料的成人化脓性脑膜炎治疗结果]

[Treatment outcome of purulent meningitis in adults from material of the Clinic of Infectious Diseases AM in Lodz in the years 1990-1991].

作者信息

Wrodycki W, Kuydowicz J, Krakowiak M, Michowicz A, Małolepsza E, Białkowska-Warzecha J, Latarska D, Hauk-Szklarek E

机构信息

Katedry i Kliniki Chorób Zakaźnych AM w Lodzi.

出版信息

Pol Tyg Lek. 1994;49(20-22):472-4.

PMID:7651918
Abstract

81 patients (pts) with bacterial meningitis hospitalised in the Clinic for Infectious Diseases in the years 1990-1991 were treated according to two therapeutic schedules. First: young pts (under 40 years), without coexisting diseases obtained Penicillin G and aminoglycoside and/or synthetic penicillin. Second: pts over 40 years old with coexisting diseases or cases of recurrent meningitis were treated with third-generation cephalosporins and aminoglycoside and/or synthetic penicillin. The mortality was 16% in the study group. 11 of 13 pts with coexisting diseases died. Neurologic sequelae were found in 23% of pts. The complete recovery was obtained in 34% of pts, more often (35.9%) in a group treated with third--generation cephalosporins comparing to 29.4% with other antibiotic therapy.

摘要

1990年至1991年间,81例细菌性脑膜炎患者在传染病诊所住院,并按照两种治疗方案进行治疗。第一:年轻患者(40岁以下),无并存疾病,给予青霉素G和氨基糖苷类药物和/或合成青霉素。第二:40岁以上有并存疾病的患者或复发性脑膜炎患者,用第三代头孢菌素和氨基糖苷类药物和/或合成青霉素治疗。研究组的死亡率为16%。13例有并存疾病的患者中有11例死亡。23%的患者出现神经后遗症。34%的患者完全康复,与接受其他抗生素治疗的患者(29.4%)相比,接受第三代头孢菌素治疗的患者更常完全康复(35.9%)。

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