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甲氧沙林与紫外线B(UVB)联合治疗与单独紫外线B辐射治疗银屑病的双侧对照研究。

Combination of methoxsalen and ultraviolet B (UVB) versus UVB radiation alone in treatment of psoriasis: a bilateral comparison study.

作者信息

Morison W L

出版信息

Photodermatol Photoimmunol Photomed. 1995 Feb;11(1):6-8. doi: 10.1111/j.1600-0781.1995.tb00129.x.

DOI:10.1111/j.1600-0781.1995.tb00129.x
PMID:7654566
Abstract

A bilateral comparison study of the therapeutic effects of broad-band ultraviolet (UBV) (FS-40 Sunlamp bulbs) radiation versus UVB radiation plus methoxsalen was conducted in patients with psoriasis. Ten patients were given up to 30 exposures to the two treatments on paired, similarly affected limbs. There was no detectable difference in the response of limbs treated with UVB plus methoxsalen versus UVB phototherapy alone although all patients did show a therapeutic response. Other areas of the body treated with methoxsalen and broad-band UVA radiation (PUVA bulbs) responded more rapidly and to a greater extent than areas exposed to UVB radiation.

摘要

在银屑病患者中进行了一项关于宽带紫外线(UBV)(FS - 40 太阳灯灯泡)辐射与中波紫外线辐射加甲氧沙林治疗效果的双侧比较研究。10 名患者在配对的、受累情况相似的肢体上接受了两种治疗,每种治疗最多照射 30 次。尽管所有患者都有治疗反应,但接受中波紫外线加甲氧沙林治疗的肢体与仅接受中波紫外线光疗的肢体在反应上没有可检测到的差异。用甲氧沙林和宽带长波紫外线辐射(PUVA 灯泡)治疗的身体其他部位比暴露于中波紫外线辐射的部位反应更快、程度更大。

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