Oppenheim M I, Sittig D F
Center for Medical Informatics, Yale University, New Haven, Connecticut 06510, USA.
Comput Biomed Res. 1995 Apr;28(2):154-70. doi: 10.1006/cbmr.1995.1011.
Automated, real-time localization of the dicrotic notch, a component of the arterial pressure waveform, represents a deceptively complex problem in computerized biomedical signal processing. The high-frequency nature of the notch can make it difficult to distinguish from artifactual noise or from other high-frequency physiological components of the waveform. In addition, the contour of the notch varies with vascular status and with propagation through arterial beds, requiring any detection algorithm to recognize various possible notch conformations. Finally, location of the notch along the waveform may vary widely depending on other hemodynamic variables, further complicating detection algorithms. We have reviewed various published algorithms and have implemented a number of them to determine the strengths and shortcomings of each. We then developed a reliable and accurate hybrid algorithm which utilizes the strengths of the various algorithmic approaches reviewed; after analyzing the waveform, the algorithm selects the most appropriate method for accurate notch localization based on a series of waveform features. The application of rule-based logic represents a relatively unique approach to digital signal processing.
自动实时定位重搏波切迹（动脉压波形的一个组成部分）在计算机化生物医学信号处理中是一个看似复杂的问题。切迹的高频特性使其难以与人为噪声或波形的其他高频生理成分区分开来。此外，切迹的轮廓会随血管状态以及在动脉床中的传播而变化，这就要求任何检测算法都能识别各种可能的切迹形态。最后，切迹在波形上的位置可能会因其他血流动力学变量而有很大差异，这进一步使检测算法变得复杂。我们回顾了各种已发表的算法，并实现了其中一些算法以确定每种算法的优缺点。然后我们开发了一种可靠且准确的混合算法，该算法利用了所回顾的各种算法方法的优点；在分析波形后，该算法根据一系列波形特征选择最合适的方法进行准确的切迹定位。基于规则的逻辑应用代表了一种相对独特的数字信号处理方法。
