Reppert S M
Laboratory of Developmental Chronobiology, Children's Service, Massachusetts General Hospital, Boston, USA.
Ciba Found Symp. 1995;183:198-207; discussion 207-11. doi: 10.1002/9780470514597.ch11.
In mammals, a unidirectional communication exists between the biological clocks of the mother and fetus. As a biological clock begins oscillating in the suprachiasmatic nuclei of the fetus, redundant circadian signals entrain the fetal clock to the prevailing light-dark cycle. Recent studies have revealed an activatable dopamine system within the fetal hypothalamus which may serve as a final common pathway by which maternal signals entrain the fetus. An entrained biological clock during fetal life makes the developing mammal better prepared for life in the outside world.