昼夜节律对大脑发育和衰老过程中健康的调节作用。
Circadian rhythms as modulators of brain health during development and throughout aging.
机构信息
Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, United States.
出版信息
Front Neural Circuits. 2023 Jan 19;16:1059229. doi: 10.3389/fncir.2022.1059229. eCollection 2022.
The circadian clock plays a prominent role in neurons during development and throughout aging. This review covers topics pertinent to the role of 24-h rhythms in neuronal development and function, and their tendency to decline with aging. Pharmacological or behavioral modification that augment the function of our internal clock may be central to decline of cognitive disease and to future chronotherapy for aging-related diseases of the central nervous system.
生物钟在神经元的发育和衰老过程中起着重要作用。这篇综述涵盖了与昼夜节律在神经元发育和功能中的作用以及它们随年龄增长而衰退的趋势相关的主题。增强我们内部生物钟功能的药理学或行为修饰可能是认知疾病衰退和未来针对中枢神经系统衰老相关疾病的时间治疗的核心。
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