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患有趾部肿物犬只的评估:117例病例(1981 - 1991年)

Evaluation of dogs with digit masses: 117 cases (1981-1991).

作者信息

Marino D J, Matthiesen D T, Stefanacci J D, Moroff S D

机构信息

Department of Surgery, Animal Medical Center, New York, NY 10021, USA.

出版信息

J Am Vet Med Assoc. 1995 Sep 15;207(6):726-8.

PMID:7657570
Abstract

Medical records of 117 dogs with digit masses were reviewed. Of 124 digit masses, 76 (61%) were malignant neoplasms, 25 (20%) were benign neoplasms, and 23 (19%) were pyogranulomatous inflammation. Of 29 digits with radiographic evidence of bone lysis, 24 (83%) were affected by malignant masses, whereas only 5 of 29 (17%) digits with radiographic evidence of bone lysis were affected by benign or pyogranulomatous masses. Only 1 of 19 (5%) dogs with melanoma had radiographic evidence of lysis, but 20 of 25 (80%) dogs with squamous cell carcinoma had radiographic evidence of bone lysis. Thoracic radiographs of 95 dogs were available. Six of 19 (32%) dogs with melanoma had radiographic evidence of pulmonary metastasis at the time of diagnosis, whereas 3 of 24 (13%) dogs with squamous cell carcinoma had radiographic evidence of pulmonary metastasis at the time of diagnosis. Twenty-nine digit neoplasms were squamous cell carcinoma, and 19 of 29 (66%) arose from the subungual epithelium. Of 19 dogs with squamous cell carcinoma originating from the subungual epithelium, 18 (95%) survived for at least 1 year, whereas only 6 of 10 (60%) dogs with squamous cell carcinoma originating in other parts of the digit survived for at least 1 year. Furthermore, of 19 dogs with squamous cell carcinoma originating from the subungual epithelium, 14 (74%) survived at least 2 years, whereas only 4 of 9 (44%) dogs with squamous cell carcinoma originating in other parts of the digit survived for 2 years. Dogs with melanoma of the digits had a median survival time of 12 months, with 10 of 24 (42%) alive at 1 year and 3 of 23 (13%) alive at 2 years.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

回顾了117只患有趾部肿物的犬的病历。在124个趾部肿物中,76个(61%)为恶性肿瘤,25个(20%)为良性肿瘤,23个(19%)为脓性肉芽肿性炎症。在29个有骨溶解影像学证据的趾部中,24个(83%)受到恶性肿物影响,而在29个有骨溶解影像学证据的趾部中,只有5个(17%)受到良性或脓性肉芽肿性肿物影响。19只患有黑色素瘤的犬中只有1只(5%)有骨溶解的影像学证据,但25只患有鳞状细胞癌的犬中有20只(80%)有骨溶解的影像学证据。95只犬有胸部X光片。19只患有黑色素瘤的犬中有6只(32%)在诊断时就有肺部转移的影像学证据,而24只患有鳞状细胞癌的犬中有3只(13%)在诊断时就有肺部转移的影像学证据。29个趾部肿瘤为鳞状细胞癌,其中19个(66%)起源于甲下上皮。在19只起源于甲下上皮的鳞状细胞癌犬中,18只(95%)存活至少1年,而在10只起源于趾部其他部位的鳞状细胞癌犬中只有6只(60%)存活至少1年。此外,在19只起源于甲下上皮的鳞状细胞癌犬中,14只(74%)存活至少2年,而在9只起源于趾部其他部位的鳞状细胞癌犬中只有4只(44%)存活2年。患有趾部黑色素瘤的犬中位生存时间为12个月,24只中有10只(42%)在1年时存活,23只中有3只(13%)在2年时存活。(摘要截选至250字)

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