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补充锌对老年糖尿病患者锌状态、铜状态及细胞免疫的影响。

Effect of zinc supplementation on zinc status, copper status and cellular immunity in elderly patients with diabetes mellitus.

作者信息

Kajanachumpol S, Srisurapanon S, Supanit I, Roongpisuthipong C, Apibal S

机构信息

Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 1995 Jul;78(7):344-9.

PMID:7658178
Abstract

This preliminary study was to investigate the effects of zinc supplementation on Zn status, Cu status, serum macrominerals and lymphocyte subsets in elderly diabetic patients. The results of Zn supplementation can correct plasma Zn levels to normal values. However, this treatment did not affect the cellular Zn, copper status and serum macrominerals. Enhancement of the percentage of CD4 cells was observed after Zn therapy but had no effect on the percentage of CD8 cells and CD4/CD8 ratios. Our finding implicated that zinc supplementation might be useful to enhance the immune status in these patients.

摘要

这项初步研究旨在调查补充锌对老年糖尿病患者锌状态、铜状态、血清常量矿物质和淋巴细胞亚群的影响。补充锌的结果可使血浆锌水平恢复到正常范围。然而,这种治疗方法对细胞内锌、铜状态和血清常量矿物质并无影响。锌治疗后观察到CD4细胞百分比有所升高,但对CD8细胞百分比和CD4/CD8比值没有影响。我们的研究结果表明,补充锌可能有助于提高这些患者的免疫状态。

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Effect of zinc supplementation on zinc status, copper status and cellular immunity in elderly patients with diabetes mellitus.补充锌对老年糖尿病患者锌状态、铜状态及细胞免疫的影响。
J Med Assoc Thai. 1995 Jul;78(7):344-9.
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Zinc homeostasis in the metabolic syndrome and diabetes.代谢综合征和糖尿病中的锌稳态。
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Zinc supplementation increases zinc status and thymopoiesis in aged mice.补充锌可提高老年小鼠的锌水平并促进胸腺生成。
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