Wu C, Yang K, Pei X, Tang A, Wang F, Wang L
Department of Experimental Hematology, Beijing Institute of Radiation Medicine, People's Republic of China.
Leuk Res. 1995 Aug;19(8):557-60. doi: 10.1016/0145-2126(95)00038-p.
It has been found recently that di-n-butyl phthalate (DBP) possesses a new pharmacological activity in the selective elimination of tumor cells from marrow. In combination with long-term liquid culture of marrow cells in vitro, DBP purged autologous bone marrow transplantation has first been applied to a case of acute myeloid leukemia at the first complete remission with successful reconstitution of hematopoiesis.
最近发现，邻苯二甲酸二正丁酯（DBP）在从骨髓中选择性清除肿瘤细胞方面具有一种新的药理活性。结合骨髓细胞的长期体外液体培养，DBP净化的自体骨髓移植首次应用于一例处于首次完全缓解期的急性髓系白血病患者，造血功能成功重建。
