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卡尔曼综合征中促卵泡生成素(FSH)和促黄体生成素(LH)对促性腺激素释放激素(LHRF)的反应

FSH and LH response to LHRF in Kallman's syndrome.

作者信息

Oettinger M, Bruneteau D W, Psaroudakis A, Greenblatt R B

出版信息

Obstet Gynecol. 1976 Feb;47(2):233-6.

PMID:765905
Abstract

The olfacto-genital syndrome (Kallman's syndrome) is believed to be primarily an hypothalamic disorder resulting in hypogonadotropic hypogonadism or hypo-ovarianism and anosmia. The pituitary response in 2 patients was measured on dialy subcutaneous injections of 100 mug of LHRF. One of the patients was also studied in a similar fashion by administration of LHRF intravenously for 4 consecutive days. A greater response occurred with the subcutaneous route.

摘要

嗅觉-生殖综合征(卡尔曼综合征)被认为主要是一种下丘脑疾病,导致促性腺激素分泌不足性性腺功能减退或卵巢功能减退以及嗅觉缺失。对2例患者每日皮下注射100微克促黄体生成素释放因子(LHRF)来测量垂体反应。其中1例患者还通过连续4天静脉注射LHRF以类似方式进行研究。皮下途径产生的反应更大。

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