近期注射纯化蛋白衍生物对感染牛分枝杆菌的牛结核病诊断试验的影响。
Effect of a recent injection of purified protein derivative on diagnostic tests for tuberculosis in cattle infected with Mycobacterium bovis.
作者信息
Doherty M L, Monaghan M L, Bassett H F, Quinn P J
机构信息
Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Ireland.
出版信息
Res Vet Sci. 1995 May;58(3):217-21. doi: 10.1016/0034-5288(95)90105-1.
PMID:7659844
Abstract
The intradermal injection of avian and bovine purified protein derivative into 15 Mycobacterium bovis-infected cattle reduced the capacity of a second single intradermal comparative tuberculin test carried out seven days later to predict accurately the animals' infection status (P < 0.001). In vitro lymphyocyte blastogenesis was also reduced (P < 0.05) but the in vitro production of interferon-gamma was unaffected.
摘要
对15头感染牛分枝杆菌的牛进行禽和牛纯化蛋白衍生物皮内注射后，7天后进行的第二次单皮内比较结核菌素试验准确预测动物感染状态的能力降低（P < 0.001）。体外淋巴细胞增殖也降低了（P < 0.05），但体外γ-干扰素的产生未受影响。
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