Marakusha B I, Rozhnova S Sh, Khristiukhina O A, Alimbekova B I, Petrovskaia V G
Zh Mikrobiol Epidemiol Immunobiol. 1995 May-Jun(3):65-70.
The study of S. enteritidis cultures of different origin, isolated at the period of 1969-1989, revealed that almost all strains isolated in 1988-1989 belonged to phagovar 1 and carried a plasmid with a molecular weight of 36 MD, while of the cultures isolated in 1969-1984 only one belonged to phagovar 1 and had a plasmid of 36 MD. All S. enteritidis strains under study, irrespective of their origin and time of isolation, were highly virulent for mice, experimentally infected by different routes. S. enteritidis cultures isolated from patients exhibited higher resistance to the bactericidal action of normal guinea pig serum than strains isolated from chickens and from water. S. enteritidis mutants having lost their plasmid of 36 MD were characterized by lower virulence for mice and guinea pigs.
对1969年至1989年期间分离出的不同来源的肠炎沙门氏菌培养物进行的研究表明,1988年至1989年分离出的几乎所有菌株都属于噬菌体型1,并携带一个分子量为36 MD的质粒,而在1969年至1984年分离出的培养物中,只有一株属于噬菌体型1且有一个36 MD的质粒。所有研究中的肠炎沙门氏菌菌株,无论其来源和分离时间如何,经不同途径实验感染小鼠后都具有高度致病性。从患者分离出的肠炎沙门氏菌培养物对正常豚鼠血清的杀菌作用表现出比从鸡和水中分离出的菌株更高的抵抗力。失去其36 MD质粒的肠炎沙门氏菌突变体对小鼠和豚鼠的致病性较低。