Osei E, Tharmaratnam S, Opemuyi I, Cochrane G
King George Hospital, Goodmayes, Essex, United Kingdom.
Acta Obstet Gynecol Scand. 1995 Sep;74(8):619-23. doi: 10.3109/00016349509013474.
To assess the effectiveness of laser endometrial ablation in women with dysfunctional bleeding.
A retrospective analysis of 90 patients.
Department of Gynaecology, King George Hospital, Barley Lane, Goodmayes, Essex IG3 8YB, U:K.
Ninety patients with dysfunctional uterine bleeding who were hysteroscopically suitable for laser endometrial ablation.
Endometrial laser ablations using the neodynium-yttrium-garnet laser at 70 watts power output.
Patient satisfaction/dissatisfaction at 6 months follow-up and response to repeat ablation.
A total of 117 procedures were carried out on the 90 patients. There was one suspected perforation which was not confirmed at subsequent hysterectomy and one primary hemorrhage which required tamponade with Foley catheter. There were three cases of fluid overload with no clinical evidence of fluid over-load syndrome. All five major complications occurred in the first six months or 'learning phase' of the study. During this period, there were proportionately more treatment failures after one attempt (52.8% versus 42.6%) than the second six months of the study. Overall, 53.3% of the patients were satisfied with the initial ablation and 73.3% were satisfied after repeat ablations.
Endometrial laser ablation is a major advance in the management of dysfunctional uterine bleeding, especially in patients who would otherwise have had a hysterectomy.
评估激光子宫内膜去除术治疗功能失调性子宫出血的有效性。
对90例患者进行回顾性分析。
英国埃塞克斯郡古德梅斯巴利巷国王乔治医院妇科,邮编IG3 8YB。
90例经宫腔镜检查适合激光子宫内膜去除术的功能失调性子宫出血患者。
使用钕钇铝石榴石激光,以70瓦的输出功率进行子宫内膜激光去除术。
随访6个月时患者的满意度/不满意情况以及再次消融的反应。
90例患者共接受了117次手术。有1例疑似穿孔,在随后的子宫切除术中未得到证实;有1例原发性出血,需要用Foley导尿管进行填塞止血。有3例出现液体超负荷,但无液体超负荷综合征的临床证据。所有5例主要并发症均发生在研究的前6个月或“学习阶段”。在此期间,首次尝试后治疗失败的比例(52.8%对42.6%)高于研究的后6个月。总体而言,53.3%的患者对初次消融满意,73.3%的患者在再次消融后满意。
激光子宫内膜去除术是功能失调性子宫出血治疗方面的一项重大进展,尤其是对于那些原本需要进行子宫切除术的患者。