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大肠杆菌cls和nov基因的鉴定。

Identity of the Escherichia coli cls and nov genes.

作者信息

Tropp B E, Ragolia L, Xia W, Dowhan W, Milkman R, Rudd K E, Ivanisević R, Savić D J

机构信息

Department of Chemistry and Biochemistry, Queens College CUNY, Flushing 11367, USA.

出版信息

J Bacteriol. 1995 Sep;177(17):5155-7. doi: 10.1128/jb.177.17.5155-5157.1995.

DOI:10.1128/jb.177.17.5155-5157.1995
PMID:7665497
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC177298/
Abstract

cls and nov mutants have similar increased sensitivities to novobiocin and reduced levels of cardiolipin, both of which can be corrected by plasmid-borne copies of either wild-type gene. A comparison of the DNA sequences of both genes further verifies their identity.

摘要

cls和nov突变体对新生霉素的敏感性均有所增加，心磷脂水平均有所降低，二者均可通过携带任一野生型基因的质粒拷贝得到纠正。对这两个基因的DNA序列进行比较进一步证实了它们的一致性。

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