Silletti R P
Division of Clinical Microbiology, City Hospital Center at Elmhurst, New York 11373, USA.
J Clin Microbiol. 1995 Jul;33(7):1829-31. doi: 10.1128/jcm.33.7.1829-1831.1995.
The CAPTIA Syphilis G enzyme-linked immunosorbent assay compared favorably with the rapid plasma reagin test when used to screen for syphilis in a low-risk population. The sensitivity and specificity of the CAPTIA Syphilis G test were 100 and 97.8%, respectively, for 646 routine specimens and 100 and 99.2%, respectively, for 265 specimens from obstetrics patients. Overall, for 911 specimens, the CAPTIA Syphilis G test showed a sensitivity of 100%, a specificity of 98.2%, and positive and negative predictive values of 78.9 and 100%, respectively. For the same population, the rapid plasma reagin test showed a sensitivity and a specificity of 96.4 and 97.5%, respectively, and positive and negative predictive values of 72 and 99.8%, respectively.
当用于低风险人群梅毒筛查时，CAPTIA梅毒G酶联免疫吸附试验与快速血浆反应素试验相比具有优势。对于646份常规标本，CAPTIA梅毒G试验的敏感性和特异性分别为100%和97.8%；对于265份产科患者标本，敏感性和特异性分别为100%和99.2%。总体而言，对于911份标本，CAPTIA梅毒G试验的敏感性为100%，特异性为98.2%，阳性预测值和阴性预测值分别为78.9%和100%。对于同一人群，快速血浆反应素试验的敏感性和特异性分别为96.4%和97.5%，阳性预测值和阴性预测值分别为72%和99.8%。
