Dunn T J, Clark V A, Jones G
Department of Anaesthetics, Eastern General Hospital, Edinburgh.
Br J Anaesth. 1995 Jul;75(1):12-4. doi: 10.1093/bja/75.1.12.
Analgesia with preoperative naproxen after laparoscopic sterilization was assessed in a prospective, double-blind, randomized study of 80 women; 42 women received oral naproxen 1 g, approximately 90 min before surgery, and 38 received placebo. Preoperative naproxen did not significantly influence postoperative pain scores, but was associated with a reduction in parenteral opioid administration (P = 0.04).
在一项针对80名女性的前瞻性、双盲、随机研究中,评估了腹腔镜绝育术前使用萘普生的镇痛效果;42名女性在手术前约90分钟口服1克萘普生,38名女性接受安慰剂。术前使用萘普生对术后疼痛评分没有显著影响,但与减少胃肠外阿片类药物的使用有关(P = 0.04)。