一名健康卵母细胞捐赠者发生严重卵巢过度刺激综合征的病例。
A case of severe ovarian hyperstimulation in a healthy oocyte donor.
作者信息
Halme J, Toma S K, Talbert L M
机构信息
North Carolina Center for Reproductive Medicine, Cary 27511, USA.
出版信息
Fertil Steril. 1995 Oct;64(4):857-9. doi: 10.1016/s0015-0282(16)57866-2.
OBJECTIVE
To report an unexpected case of severe ovarian hyperstimulation syndrome (OHSS) and to compare E2 levels and number of follicles to other oocyte donors.
SETTING
Private assisted reproduction technology center.
PATIENTS
Healthy oocyte donors with normal menstrual cyclicity.
INTERVENTIONS
Prophylactic and therapeutic use of human serum albumin infusions.
MAIN OUTCOME MEASURE
The clinical development of signs and symptoms of severe OHSS.
RESULTS
More than 60% of other oocyte donors had higher E2 levels and 12% had higher number of follicles without associated OHSS.
CONCLUSION
The risk of developing severe OHSS cannot be predicted accurately to be low even in the absence of "risk factors."
目的
报告一例意外发生的严重卵巢过度刺激综合征（OHSS）病例，并将雌激素（E2）水平和卵泡数量与其他卵母细胞捐赠者进行比较。
地点
私立辅助生殖技术中心。
患者
月经周期正常的健康卵母细胞捐赠者。
干预措施
预防性和治疗性使用人血清白蛋白输注。
主要观察指标
严重OHSS体征和症状的临床发展情况。
结果
超过60%的其他卵母细胞捐赠者E2水平更高，12%的捐赠者卵泡数量更多，但均未发生相关OHSS。
结论
即使不存在“风险因素”，也不能准确预测发生严重OHSS的风险较低。
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