Lewit N, Kol S, Ronen N, Itskovitz-Eldor J
Department of Obsterics and Gynecology, Rambam Medical Center, Haifa, Israel.
Fertil Steril. 1996 Oct;66(4):654-6. doi: 10.1016/s0015-0282(16)58584-7.
To report our experience with i.v. albumin as a means to prevent ovarian hyperstimulation syndrome (OHSS) in high-risk patients.
Retrospective case-series.
University hospital-based IVF program.
Five women undergoing controlled ovarian stimulation for IVF-Based on previous history and/or E2 measurements and number of ovarian follicles, these patients were considered to be at high risk for developing OHSS.
Intravenous albumin was given at the time of oocyte retrieval. Additional doses were given 12 and 24 hours later.
Development of OHSS.
Four patients developed OHSS; two of them had the severe form of the syndrome.
Severe OHSS may develop in high-risk patients despite the prophylactic administration of i.v. albumin.
报告我们使用静脉注射白蛋白预防高危患者卵巢过度刺激综合征（OHSS）的经验。
回顾性病例系列研究。
大学附属医院的体外受精项目。
5名接受体外受精控制性卵巢刺激的女性。基于既往病史和/或雌二醇测量值以及卵巢卵泡数量，这些患者被认为发生OHSS的风险较高。
在取卵时给予静脉注射白蛋白。在12小时和24小时后给予额外剂量。
OHSS的发生情况。
4名患者发生了OHSS；其中2名患有严重形式的该综合征。
尽管预防性给予静脉注射白蛋白，高危患者仍可能发生严重OHSS。
