Kihira C, Mizutani H, Shimizu M
Department of Dermatology, Mie University School of Medicine, Japan.
J Dermatol. 1995 May;22(5):357-9. doi: 10.1111/j.1346-8138.1995.tb03404.x.
We report a case of progressive systemic sclerosis (PSS) who suddenly developed sinus arrest during an operation for gastric cancer under general anesthesia. No abnormalities in her cardiac, respiratory or renal functions had been detected before surgery. The cardiac functions evaluated by echocardiogram before and after pacemaking eliminated heart muscular involvement. We speculated that the operation stress induced by general anesthesia altered the asymptomatic fibrotic sinus into apparent sinus dysfunction. Care should be taken in general anesthesia for scleroderma patients who are free from detectable cardiac manifestations.
我们报告一例进行性系统性硬化症（PSS）患者，该患者在全身麻醉下进行胃癌手术时突然发生窦性停搏。术前未检测到其心脏、呼吸或肾功能异常。通过起搏器植入前后的超声心动图评估心脏功能，排除了心肌受累情况。我们推测全身麻醉引起的手术应激将无症状的纤维化窦房结改变为明显的窦房结功能障碍。对于无明显心脏表现的硬皮病患者，全身麻醉时应谨慎操作。
