Rogers F B, Shackford S R, Keller M S
College of Medicine, University of Vermont, Burlington 05405, USA.
J Trauma. 1995 Aug;39(2):261-5. doi: 10.1097/00005373-199508000-00012.
To determine the effect of the timing of fracture fixation and the physiologic status on admission of elderly patients with hip fractures from low impact falls on resource utilization and outcome.
A 5-year retrospective review of 82 elderly (age > 65 years) patients with isolated low-impact hip fractures stratified into early (< 24 hours), intermediate (24 to 72 hours), and late (> 72 hours) operative fixation. Admission Acute Physiology and Chronic Health Evaluation (APACHE) II scores, number of comorbidities, fracture type, complication rate, length of stay, discharge acuity, and mortality were calculated for each group.
Values are mean +/- SD. The mean admission APACHE II score of the entire group was 8.1 +/- 0.2, indicating that these patients were physiologically stable on arrival. The mean numbers of comorbidities or APACHE II were not significant between groups. No differences existed in the mean APACHE II scores for survivors and nonsurvivors (7.95 +/- 2.34 vs. 9.17 +/- 3.06, p = 0.2409). There were no differences in the mean APACHE II scores and predicted survival for each group. However, a significant decrease in actual survival was observed with late fixation (p < 0.001; Fisher's Exact Test). Patients who were fixed late also had a significantly higher infectious morbidity (p = 0.00469), length of stays (p = 0.0226), and total hospital cost (p = 0.0001), compared with those fixed early or immediate, despite having no difference in average acuity upon discharge (p = 0.3883).
Delay in fracture fixation, in elderly patients who are physiologically stable on admission, significantly increases morbidity and mortality and adversely affects resource utilization.
确定骨折固定时机及入院时的生理状态对低能量跌倒所致老年髋部骨折患者资源利用和预后的影响。
对82例年龄大于65岁、因低能量跌倒导致孤立性髋部骨折的老年患者进行为期5年的回顾性研究,将患者分为早期(<24小时)、中期(24至72小时)和晚期(>72小时)手术固定组。计算每组患者入院时的急性生理与慢性健康状况评估(APACHE)II评分、合并症数量、骨折类型、并发症发生率、住院时间、出院时的病情严重程度及死亡率。
数据以均数±标准差表示。整个研究组的平均入院APACHE II评分为8.1±0.2,表明这些患者入院时生理状态稳定。各组间合并症数量或APACHE II评分的均值无显著差异。存活患者与非存活患者的平均APACHE II评分无差异(7.95±2.34对9.17±3.06,p = 0.2409)。每组的平均APACHE II评分及预测生存率无差异。然而,晚期固定患者的实际生存率显著降低(p < 0.001;Fisher精确检验)。尽管出院时平均病情严重程度无差异(p = 0.3883),但与早期或即刻固定的患者相比,晚期固定的患者感染发病率显著更高(p = 0.00469)、住院时间更长(p = 0.0226)且总住院费用更高(p = 0.0001)。
对于入院时生理状态稳定的老年患者,骨折固定延迟会显著增加发病率和死亡率,并对资源利用产生不利影响。