血糖的家庭监测。改善糖尿病控制的方法。

Home monitoring of blood-glucose. Method for improving diabetic control.

作者信息

Sönksen P H, Judd S L, Lowy C

出版信息

Lancet. 1978 Apr 8;1(8067):729-32. doi: 10.1016/s0140-6736(78)90854-1.

Abstract

64 diabetic patients measured their own blood-glucose concentration with "Dextrostix' (Ames) and an 'Eyetone' (Ames) meter. The records made at home by 53 of these patients have shown that this led to a significant improvement in blood-glucose control. A majority (64%) were able to maintain "good" control (80% of blood-glucose recordings equal to or less than 10 mmol/l for periods as long as 478 days). This hitherto unobtainable degree of control of blood-glucose was achieved mostly with conventional insulin regimens of twice-daily 'Actrapid' (Novo Laboratories Ltd.) and 'Leo-Retard' (Leo Laboratories Ltd.). Adjustments of insulin dosage and type were found to be much easier and more predictable than with urine-glucose analysis. No significant complications were encountered. Hypoglycaemic episodes were less frequent. 70% of patients preferred blood-tests to urine tests and 92% would like to buy their own meter "if the price was right." The results suggest that self-monitoring of blood-glucose by diabetics makes possible, for the first time, the achievement of near normoglycaemia. This may reduce the incidence of long-term diabetic complications.

摘要

64名糖尿病患者使用“Ames公司的‘Dextrostix’血糖仪和‘Eyetone’血糖仪自行测量血糖浓度。其中53名患者在家中的记录显示，这使得血糖控制有了显著改善。大多数患者（64%）能够维持‘良好’的控制水平（在长达478天的时间里，80%的血糖记录等于或低于10毫摩尔/升）。这种迄今为止难以实现的血糖控制程度主要是通过每日两次注射‘Actrapid’（诺和诺德公司）和‘Leo-Retard’（利奥制药公司）的常规胰岛素治疗方案实现的。与尿糖分析相比，发现胰岛素剂量和类型的调整更加容易且更可预测。未出现明显并发症。低血糖发作次数减少。70%的患者更喜欢血糖检测而非尿糖检测，92%的患者表示‘如果价格合适’愿意购买自己的血糖仪。结果表明，糖尿病患者自行监测血糖首次使得实现接近正常血糖水平成为可能。这可能会降低长期糖尿病并发症的发生率。