Hermanek P, Wittekind C
Department of Surgery, University of Erlangen, Germany.
World J Surg. 1995 Jul-Aug;19(4):491-5. doi: 10.1007/BF00294707.
Tumor classification is associated with two inherent problems: (1) to find a compromise between the simplicity needed for a wide application by the medical community and sufficient differentiation and specification required for the presently high differentiation in treatment options and for detailed analysis of treatment results; and (2) to achieve an agreement between the stability necessary for data collection over long periods and the needed continuous inclusion of new proposals that arise by advances in diagnostic and therapeutic methods and the increasing knowledge of prognostic factors. The aim of this report is to inform on the changes and expansions of the international classification of gastric carcinoma during the last few years, to refer to new developments, to point out the relations between established classifications and molecular biology, and to show the future trend in tumor classification.
（1）在医学领域广泛应用所需的简单性与当前治疗选择高度分化以及治疗结果详细分析所需的充分区分和细化之间找到平衡；（2）在长期数据收集所需的稳定性与因诊断和治疗方法的进步以及预后因素知识的增加而不断纳入新提议之间达成一致。本报告的目的是介绍过去几年国际胃癌分类的变化和扩展，提及新进展，指出既定分类与分子生物学之间的关系，并展示肿瘤分类的未来趋势。
