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心肌保护当前技术的最新进展。

Update on current techniques of myocardial protection.

作者信息

Buckberg G D

机构信息

Department of Surgery, University of California, School of Medicine, Los Angeles, USA.

出版信息

Ann Thorac Surg. 1995 Sep;60(3):805-14. doi: 10.1016/0003-4975(95)00572-3.

Abstract

The spectrum of strategies for myocardial protection has led to the artificial creation of adversarial positions in regard to warm versus cold blood cardioplegia, antegrade versus retrograde delivery, and intermittent versus continuous perfusion. This report reviews the background for the aforementioned methods, that has led to the evolution of an integrated myocardial management technique that combines the advantages of the aforementioned methods to compensate for their individual shortcomings. This approach coordinates the myocardial protective strategies with the continuity of the operation so that the surgical procedure is never interrupted. It provides unimpaired vision, avoids unnecessary ischemia and cardioplegic overdose, allows aortic clamping as soon as cardiopulmonary bypass is started, permits aortic unclamping and discontinuation of bypass shortly after the technical procedure is completed, and minimizes the ration of ischemia and cardiopulmonary bypass. The preliminary results in 1,474 patients from four centers with surgeons participating in the infrastructure of this method are presented.

摘要

心肌保护策略的范围导致了在温血与冷血心脏停搏、顺行与逆行给药以及间歇性与持续性灌注方面人为地形成了对立立场。本报告回顾了上述方法的背景,这些背景促成了一种综合心肌管理技术的发展,该技术结合了上述方法的优点以弥补其各自的缺点。这种方法将心肌保护策略与手术的连续性相协调,从而使手术过程不会中断。它提供清晰的视野,避免不必要的缺血和心脏停搏液过量,允许在体外循环开始后立即进行主动脉阻断,在技术操作完成后不久允许主动脉开放和体外循环停止,并将缺血和体外循环的时间比降至最低。本文介绍了来自四个中心的1474例患者的初步结果,外科医生参与了该方法的实施。

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