Kazantseva I A, Kalinin A P, Poliakova G A, Davydova I V, Tikhomirov O Iu
Arkh Patol. 1995 May-Jun;57(3):31-5.
Surgical material from 51 patients operated on for insulinoma is studied. Three histological variants of insulinoma are distinguished: adenoma-like, insular-ductal and carcinoid-like. The structure of Langerhans islands outside the tumour is described and the diagnostic criteria of insuloma-microadenoma are presented. Multiple nests of the endocrine cells are regarded either as a manifestation of the multifocal island pathology or as a marker of non-diagnosed insuloma. There is a need of distinguishing between the terms related to the nosology and histogenesis of endocrine pancreatic tumours.
对51例因胰岛素瘤接受手术的患者的手术材料进行了研究。区分出胰岛素瘤的三种组织学变体：腺瘤样、岛状导管样和类癌样。描述了肿瘤外朗格汉斯岛的结构，并提出了胰岛素瘤微腺瘤的诊断标准。内分泌细胞的多个巢被视为多灶性胰岛病变的表现或未确诊胰岛素瘤的标志物。有必要区分与胰腺内分泌肿瘤的疾病分类学和组织发生学相关的术语。
