Mostofi F K, Sesterhenn I A, Davis C J
Department of Genitourinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
Cancer. 1993 Feb 1;71(3 Suppl):906-32. doi: 10.1002/1097-0142(19930201)71:3+<906::aid-cncr2820711407>3.0.co;2-i.
In this article, the pathologic findings of carcinoma of the prostate were reviewed. Criteria were discussed for the pathologic diagnosis of prostatic carcinoma (PC), premalignant lesions, lesions that simulate PC, immunopathologic findings, special types of PC, effects of therapy on the prostate, and recent efforts to improve diagnostic and prognostic capabilities. The possible role of the study of nucleolar organizing regions was reported. A new method for demonstrating chromosomes in formaldehyde-fixed paraffin-embedded tissue was mentioned. The need for research in all aspects of the pathology of prostatic cancer was emphasized.
本文回顾了前列腺癌的病理检查结果。讨论了前列腺癌（PC）病理诊断的标准、癌前病变、疑似PC的病变、免疫病理检查结果、PC的特殊类型、治疗对前列腺的影响以及近期在提高诊断和预后能力方面所做的努力。报道了核仁组织区研究的可能作用。提及了一种在甲醛固定石蜡包埋组织中显示染色体的新方法。强调了对前列腺癌病理学各个方面进行研究的必要性。
