Ulbig M W, McHugh D A, Hamilton A M
Retinal Diagnostic Department, Moorfields Eye Hospital, London.
Br J Ophthalmol. 1993 Apr;77(4):218-21. doi: 10.1136/bjo.77.4.218.
Nine eyes with parafoveal choroidal neovascular membranes due to age-related macular degeneration or angioid streaks were treated with a diode laser and were followed up to 40 weeks (mean 26 weeks). Angiographically proved closure of the membrane was achieved in seven eyes. Four lesions needed a second treatment for growth of subretinal neovascular tissue. Post-treatment visual acuity ranged from 6/9 to 6/60. Two eyes developed subfoveal membranes resulting in poor visual acuity. The morphology of the diode laser lesions differed from that of the argon green laser and was more similar to that of the krypton laser, producing a 'black hole' on the fluorescein positive print. In one particular eye fluorescein angiography revealed subfoveal choroidal non-perfusion next to the site of the diode lesion suggesting choroidal vascular closure.
9只因年龄相关性黄斑变性或血管样条纹导致的黄斑旁脉络膜新生血管膜的眼睛接受了二极管激光治疗，并随访至40周（平均26周）。7只眼睛经血管造影证实新生血管膜封闭。4个病灶因视网膜下新生血管组织生长需要二次治疗。治疗后视力范围为6/9至6/60。2只眼睛出现黄斑下膜，导致视力不佳。二极管激光病灶的形态与氩绿激光不同，更类似于氪激光，在荧光素阳性照片上产生一个“黑洞”。在一只特定的眼睛中，荧光素血管造影显示在二极管病灶部位旁边有黄斑下脉络膜无灌注，提示脉络膜血管封闭。
