Oliver G F, Winkelmann R K
Gilgit Road Specialist Centre, Auckland, New Zealand.
Drugs. 1993 Jan;45(1):56-65. doi: 10.2165/00003495-199345010-00006.
Lichen planus is an inflammatory pruritic dermatosis in which T lymphocytes attack the basal epidermis, producing characteristic clinical and histological lesions. Mild cases can be treated successfully with rest, topical corticosteroids with or without wet dressings, or occlusion. Severe generalised cases may require systemic corticosteroids. Chronic, aggressive lesions may need additional therapy ranging from psoralen plus ultraviolet A (PUVA) to retinoids or cyclosporin. Complications ranging from infectious, bullous disease or ulceration require special treatment considerations.
扁平苔藓是一种炎症性瘙痒性皮肤病,其中T淋巴细胞攻击基底表皮,产生特征性的临床和组织学病变。轻度病例通过休息、外用糖皮质激素(有或没有湿敷)或封包治疗可成功治愈。严重的全身性病例可能需要全身性糖皮质激素治疗。慢性、侵袭性病变可能需要从补骨脂素加紫外线A(PUVA)到维甲酸或环孢素等额外治疗。感染、大疱性疾病或溃疡等并发症需要特殊的治疗考虑。