Gordon C R, Oksenberg A
Department of Neurology, Beilinson Medical Center, Petah Tiqva, Israel.
Electroencephalogr Clin Neurophysiol. 1993 Feb;86(2):132-7. doi: 10.1016/0013-4694(93)90085-a.
The presence of spontaneous CNS nystagmus during wakefulness was documented for the first time in 6 vegetative-state (VS) patients. Nystagmus of smaller amplitude as compared to the awake state was consistently detected in each patient during stage 1 of sleep. There was complete absence of nystagmus during stage 2 and slow wave sleep (SWS) in all the patients. Clear nystagmus episodes were observed during rapid eye movement (REM) sleep in all patients. Some nystagmus episodes followed rapid eye movements (REMs), some were unrelated to REMs while others were superimposed on REMs. It is suggested that spontaneous neural activation during REM sleep may allow the episodic emergence of nystagmus during this sleep stage.
首次在6名植物人状态（VS）患者中记录到清醒时出现自发性中枢性眼球震颤。与清醒状态相比，在每个患者的睡眠第1阶段均持续检测到幅度较小的眼球震颤。所有患者在睡眠第2阶段和慢波睡眠（SWS）期间均完全没有眼球震颤。在所有患者的快速眼动（REM）睡眠期间均观察到明显的眼球震颤发作。一些眼球震颤发作跟随快速眼动（REM），一些与REM无关，而另一些则叠加在REM上。提示REM睡眠期间的自发性神经激活可能使该睡眠阶段出现间歇性眼球震颤。
