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猪鼻支原体中的抗原变异：可变脂蛋白库增加，扩展了表面多样性和结构复杂性。

Antigenic variation in Mycoplasma hyorhinis: increased repertoire of variable lipoproteins expanding surface diversity and structural complexity.

作者信息

Rosengarten R, Theiss P M, Yogev D, Wise K S

机构信息

Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri-Columbia 65212.

出版信息

Infect Immun. 1993 May;61(5):2224-8. doi: 10.1128/iai.61.5.2224-2228.1993.

DOI:10.1128/iai.61.5.2224-2228.1993
PMID:7683004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC280828/
Abstract

VlpE is characterized as a new member in a family of variable surface lipoproteins (Vlps) of Mycoplasma hyorhinis. VlpE shows phenotypic variation in expression and size within isogenic lineages of some strains but is absent from lineages of other strains that express only three previously known Vlps. Expression of four Vlps in some cells further indicates the presence and usage of an expanded reservoir of Vlp coding sequences, which greatly increases the capacity for surface diversification.

摘要

VlpE被鉴定为猪鼻支原体可变表面脂蛋白（Vlp）家族中的一个新成员。VlpE在一些菌株的同基因谱系中表现出表达和大小的表型变异，但在仅表达三种先前已知Vlp的其他菌株谱系中不存在。在一些细胞中四种Vlp的表达进一步表明存在并使用了Vlp编码序列的扩展库，这大大增加了表面多样化的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/a25d5b55b4b5/iai00017-0643-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/1bcfb83331ba/iai00017-0641-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/1048dde7d339/iai00017-0642-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/3911945b8aaa/iai00017-0642-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/a25d5b55b4b5/iai00017-0643-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/1bcfb83331ba/iai00017-0641-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/1048dde7d339/iai00017-0642-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/3911945b8aaa/iai00017-0642-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54b0/280828/a25d5b55b4b5/iai00017-0643-a.jpg

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Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene.
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