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雌激素和孕激素受体在人子宫内膜及输卵管中的分布。一项免疫细胞化学研究。

Topographical distribution of oestrogen and progesterone receptors in the human endometrium and fallopian tube. An immunocytochemical study.

作者信息

Coppens M T, de Boever J G, Dhont M A, Serreyn R F, Vandekerckhove D A, Roels H J

机构信息

N. Goormaghtigh Institute of Pathology Universitair Ziekenhuis, Ghent, Belgium.

出版信息

Histochemistry. 1993 Feb;99(2):127-31. doi: 10.1007/BF00571873.

DOI:10.1007/BF00571873
PMID:7683010
Abstract

The topographical distribution of oestrogen and progesterone receptors in the human endometrium and Fallopian tube was investigated by an immunocytochemical technique. A gradient of positively stained cells was observed: the highest oestrogen and progesterone receptor content was noted in the fundal part of the uterine cavity and the ampullar region of the Fallopian tube. The observed gradient is in keeping with biological and pathological events that occur in the human mullerian tract, e.g. fecundation, implantation and carcinogenesis.

摘要

采用免疫细胞化学技术研究了雌激素和孕激素受体在人子宫内膜及输卵管中的分布情况。观察到阳性染色细胞呈梯度分布:子宫腔底部及输卵管壶腹部的雌激素和孕激素受体含量最高。所观察到的梯度与人类苗勒管发生的生物学及病理学事件相符,如受精、着床及致癌作用。

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本文引用的文献

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A comparison of cytoplasmic and nuclear estradiol and progesterone receptors in human fallopian tube and endometrial tissue.人输卵管和子宫内膜组织中细胞质及细胞核雌二醇和孕酮受体的比较。
Fertil Steril. 1981 Nov;36(5):615-22. doi: 10.1016/s0015-0282(16)45860-7.
2
Monoclonal antibodies to human estrogen receptor.抗人雌激素受体单克隆抗体。
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5115-9. doi: 10.1073/pnas.77.9.5115.
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Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells.单克隆抗体将雌激素受体定位在靶细胞核中。
基于绝经时间的绝经后妇女输卵管中雌激素和孕激素受体免疫表达。
Int J Environ Res Public Health. 2021 Aug 31;18(17):9195. doi: 10.3390/ijerph18179195.
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Attenuated sex steroid receptor expression in fallopian tube of women with ectopic pregnancy.异位妊娠患者输卵管中减弱的性激素受体表达。
J Clin Endocrinol Metab. 2009 Dec;94(12):5146-54. doi: 10.1210/jc.2009-1476. Epub 2009 Oct 28.
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An immunocytochemical method for demonstrating estrogen receptor in human uterus using monoclonal antibodies to human estrophilin.一种使用抗人雌激素受体单克隆抗体在人子宫中显示雌激素受体的免疫细胞化学方法。
Lab Invest. 1984 Apr;50(4):480-6.
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The measurement of high-affinity oestradiol receptors in human uterine endometrium and myometrium.人子宫内膜和子宫肌层中高亲和力雌二醇受体的测定。
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Am J Pathol. 1986 May;123(2):280-92.
7
Distribution of cytoplasmic estrogen and progesterone receptors in human endometrium.人子宫内膜中细胞质雌激素和孕激素受体的分布
Am J Obstet Gynecol. 1978 Oct 15;132(4):449-54. doi: 10.1016/0002-9378(78)90783-4.