Schvarcz J R
J Neurol Neurosurg Psychiatry. 1976 Jan;39(1):53-7. doi: 10.1136/jnnp.39.1.53.
A procedure is reported in which radiofrequency lesions were stereotactically placed in the central cord region at the cervicomedullary junction to interrupt selectively the extralemniscal system. Physiological recognition of the target site was based upon the homuncular organization of the dorsal funiculi, which is analysed. Only subjective (segmentally unrelated) analgesia was achieved, usually without demonstrable sensory loss. Stimuli were not painful, while ability to localize it and the discrimination between sharp and blunt components were preserved. A rational approach is offered to certain central pain phenomena which resulted in abolition of hyperpathia and disappearance of, or marked reduction in, deep background pain. Both upper and lower body pain were easily dealt with. Pathways for automatic respiration or for micturition were not encroached upon. Therefore it was electively used for cases with diminished respiratory reserve and for cases with midline and/or bilateral pain.
本文报道了一种手术方法,即通过立体定向将射频损伤置于颈髓交界处的脊髓中央区域,以选择性地阻断脊髓丘脑外系统。对靶点的生理识别基于对背索躯体感觉定位组织的分析。仅实现了主观(与节段无关)镇痛,通常无明显感觉丧失。刺激不产生疼痛,同时定位能力以及区分锐性和钝性刺激成分的能力得以保留。对于某些中枢性疼痛现象,该方法提供了一种合理的治疗途径,可消除痛觉过敏,并使深部背景性疼痛消失或显著减轻。上下半身的疼痛均易于处理。自动呼吸或排尿通路未受影响。因此,该方法被选择性地用于呼吸储备功能减退的病例以及中线和/或双侧疼痛的病例。