Gupta A, Agarwal A, Bansal R K, Agarwal A, Chugh K S
Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Eye (Lond). 1993;7 ( Pt 1):138-42. doi: 10.1038/eye.1993.29.
Little is known about the behaviour of central retinal vein occlusion (CRVO) in the young. We studied the course and visual outcome in 25 patients with CRVO aged less than 40 years with special reference to the association with underlying systemic disorders. Eight patients had ischaemic CRVO while 17 had non-ischaemic CRVO. Systemic disorders associated with ischaemic CRVO included end-stage renal disease in 3, and hypercholesterolaemia, beta-thalassaemia and hypertension in 1 each. All patients with ischaemic CRVO had unusually severe disease and a rapid downhill course. Management included panretinal photocoagulation in 7 eyes, trabeculectomy with 5-fluorouracil in 3 eyes and cyclocryopexy in 2 eyes. Despite this 3 eyes became phthisical and the final visual acuity in all eyes ranged from no light perception to 6/60. Three patients with end-stage renal disease died within 15 months of diagnosis of venous occlusion.
关于年轻患者视网膜中央静脉阻塞（CRVO）的表现，人们所知甚少。我们研究了25例年龄小于40岁的CRVO患者的病程和视力转归，特别关注其与潜在全身性疾病的关联。8例为缺血性CRVO，17例为非缺血性CRVO。与缺血性CRVO相关的全身性疾病包括3例终末期肾病，以及各1例高胆固醇血症、β地中海贫血和高血压。所有缺血性CRVO患者病情均异常严重且病程迅速恶化。治疗包括7只眼行全视网膜光凝，3只眼行小梁切除术联合5-氟尿嘧啶，2只眼行睫状体冷凝术。尽管如此，仍有3只眼眼球萎缩，所有患眼的最终视力范围从无光感到6/60。3例终末期肾病患者在静脉阻塞诊断后的15个月内死亡。
