Simak R, Madersbacher S, Zhang Z F, Maier U
Department of Urology, University of Vienna Medical School, Austria.
J Urol. 1993 Sep;150(3):895-7. doi: 10.1016/s0022-5347(17)35642-2.
In a pilot study including 18 patients between 20 and 39 years old serum prostate specific antigen (PSA) was evaluated before as well as 1 and 7 days after ejaculation. In 13 patients who had more than 0 ng./ml. PSA before ejaculation (mean 1.44 ng./ml.) there were statistically significant decreases in serum PSA down to 0.17 ng./ml. and 0.29 ng./ml., respectively (p = 0.0001). These results suggest a physiological relationship between ejaculation and decreased serum PSA levels. Due to the clinical significance of PSA in the diagnosis and monitoring of prostate cancer, further studies are needed including men of risk age and untreated prostate cancer patients.
在一项纳入18名年龄在20至39岁之间患者的初步研究中，在射精前以及射精后1天和7天对血清前列腺特异性抗原（PSA）进行了评估。在射精前PSA超过0 ng/ml的13名患者中（平均1.44 ng/ml），血清PSA分别显著下降至0.17 ng/ml和0.29 ng/ml（p = 0.0001）。这些结果表明射精与血清PSA水平降低之间存在生理关系。由于PSA在前列腺癌诊断和监测中的临床意义，需要开展进一步研究，纳入高危年龄男性和未经治疗的前列腺癌患者。
