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射精对血清前列腺特异性抗原水平的影响。

The influence of ejaculation on serum levels of prostate specific antigen.

作者信息

Heidenreich A, Vorreuther R, Neubauer S, Westphal J, Engelmann U H, Moul J W

机构信息

Department of Urology, University of Cologne, Germany.

出版信息

J Urol. 1997 Jan;157(1):209-11.

PMID:8976253
Abstract

PURPOSE

While prostatic manipulation and surgery have been shown to increase serum prostate specific antigen (PSA), the influence of ejaculation on serum PSA remains controversial. We examined the effect of ejaculation on serum PSA levels.

MATERIALS AND METHODS

We evaluated 100 men 25 to 35 years old with no history of surgery or inflammatory disease of the urogenital tract. Serum PSA was evaluated 1 and 24 hours after ejaculation, and serum testosterone and seminal fluid PSA levels were determined.

RESULTS

In all men a baseline PSA level was detected. There were no statistically significant changes in serum PSA and testosterone 1 and 24 hours after ejaculation. Mean PSA concentration was significantly higher in seminal plasma than in serum. However, we did not observe a correlation between serum and seminal plasma PSA levels.

CONCLUSIONS

Based on our data ejaculation does not affect serum PSA concentration in young men, and there seems to be no physiological relationship between ejaculation and PSA level.

摘要

目的

虽然前列腺按摩和手术已被证明会使血清前列腺特异性抗原(PSA)升高,但射精对血清PSA的影响仍存在争议。我们研究了射精对血清PSA水平的影响。

材料与方法

我们评估了100名年龄在25至35岁之间、无手术史或泌尿生殖道炎症疾病史的男性。在射精后1小时和24小时评估血清PSA,并测定血清睾酮和精液PSA水平。

结果

所有男性均检测到基线PSA水平。射精后1小时和24小时,血清PSA和睾酮无统计学显著变化。精液中PSA的平均浓度显著高于血清中的PSA。然而,我们未观察到血清和精液中PSA水平之间的相关性。

结论

根据我们的数据,射精不影响年轻男性的血清PSA浓度,射精与PSA水平之间似乎不存在生理关系。

相似文献

1
The influence of ejaculation on serum levels of prostate specific antigen.射精对血清前列腺特异性抗原水平的影响。
J Urol. 1997 Jan;157(1):209-11.
2
Ejaculation increases the serum prostate-specific antigen concentration.射精会使血清前列腺特异性抗原浓度升高。
Urology. 1996 Apr;47(4):511-6. doi: 10.1016/S0090-4295(99)80486-5.
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Effect of ejaculation on serum total and free prostate-specific antigen concentrations.射精对血清总前列腺特异性抗原和游离前列腺特异性抗原浓度的影响。
Urology. 1997 Aug;50(2):239-43. doi: 10.1016/S0090-4295(97)00209-4.
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Serum and semen prostate specific antigen concentrations are different in young spinal cord injured men compared to normal controls.与正常对照组相比,年轻脊髓损伤男性的血清和精液前列腺特异性抗原浓度有所不同。
J Urol. 1999 Jul;162(1):89-91. doi: 10.1097/00005392-199907000-00022.
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Postejaculation serum prostate-specific antigen level.射精后血清前列腺特异性抗原水平。
Eur Urol. 1997;32(1):54-7.
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Blood levels of free-PSA but not complex-PSA significantly correlates to prostate release of PSA in semen in young men, while blood levels of complex-PSA, but not free-PSA increase with age.在年轻男性中,游离前列腺特异性抗原(free-PSA)而非复合前列腺特异性抗原(complex-PSA)的血液水平与精液中前列腺特异性抗原(PSA)的前列腺分泌显著相关,而复合前列腺特异性抗原的血液水平随年龄增长而升高,游离前列腺特异性抗原则不然。
Prostate. 2005 Sep 15;65(1):66-72. doi: 10.1002/pros.20254.
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Correlation between simultaneous PSA and serum testosterone concentrations among eugonadal, untreated hypogonadal and hypogonadal men receiving testosterone replacement therapy.性腺功能正常、未经治疗的性腺功能减退以及接受睾酮替代治疗的性腺功能减退男性中,同时检测的前列腺特异性抗原(PSA)与血清睾酮浓度之间的相关性。
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Prostate-specific antigen changes and prostate cancer in hypogonadal men treated with testosterone replacement therapy.接受睾酮替代疗法的性腺功能减退男性的前列腺特异性抗原变化与前列腺癌
BJU Int. 2009 May;103(9):1179-83. doi: 10.1111/j.1464-410X.2008.08240.x. Epub 2008 Dec 23.
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Physiologic variations of serum testosterone within the normal range do not affect serum prostate-specific antigen.血清睾酮在正常范围内的生理变化不会影响血清前列腺特异性抗原。
Urology. 1995 Jul;46(1):58-61. doi: 10.1016/S0090-4295(99)80159-9.
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The role of prostate-specific antigen in the chemoprevention of prostate cancer.前列腺特异性抗原在前列腺癌化学预防中的作用。
J Cell Biochem Suppl. 1996;25:149-55.

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