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孟加拉国和日本献血者丙型肝炎血清流行病学比较。

Comparison of seroepidemiology of hepatitis C in blood donors between Bangladesh and Japan.

作者信息

Khan M, Husain M, Yano M, Hashizume K, Yousuf M, Tanaka E, Matsumoto A, Furuta S, Kiyosawa K

机构信息

Department of Internal Medicine, Institute of Post Graduate Medicine and Research, Dhaka, Bangladesh.

出版信息

Gastroenterol Jpn. 1993 May;28 Suppl 5:28-31. doi: 10.1007/BF02989200.

DOI:10.1007/BF02989200
PMID:7689505
Abstract

To compare the seroepidemiology of hepatitis C and hepatitis B between Bangladesh and Japan, we tested the second generation antibody to hepatitis C virus (anti-HCV-2) and hepatitis B surface antigen (HBsAg) in serum samples from 163 professional blood donors (161 males and 2 females, mean age 28.6 yr.) and 83 voluntary blood donors from Bangladesh, and 7479 Japanese voluntary blood donors (5036 males and 2443 females; mean age 37.1 yr.). In Bangladesh, anti-HCV-2 is detected in 2.4% of professional blood donors and 0% of voluntary blood donors, furthermore, HBsAg is detected in 29% and in 2.4% of professional and voluntary blood donors, respectively. In Japan, anti-HCV-2 is detected in 0.6% in voluntary blood donors, and HBsAg also in 0.6%. These results indicate that professional blood donors in Bangladesh are highly contaminated by hepatitis B virus and moderately by hepatitis C virus, while voluntary blood donors in both countries are not so highly contaminated by either hepatitis viruses.

摘要

为比较孟加拉国和日本丙型肝炎与乙型肝炎的血清流行病学,我们检测了163名职业献血者(161名男性和2名女性,平均年龄28.6岁)和83名来自孟加拉国的志愿献血者以及7479名日本志愿献血者(5036名男性和2443名女性;平均年龄37.1岁)血清样本中的第二代丙型肝炎病毒抗体(抗-HCV-2)和乙型肝炎表面抗原(HBsAg)。在孟加拉国,2.4%的职业献血者检测到抗-HCV-2,志愿献血者中该比例为0%;此外,职业献血者和志愿献血者中HBsAg的检测率分别为29%和2.4%。在日本,志愿献血者中抗-HCV-2的检测率为0.6%,HBsAg的检测率也为0.6%。这些结果表明,孟加拉国的职业献血者受乙型肝炎病毒高度污染,受丙型肝炎病毒中度污染,而两国的志愿献血者受这两种肝炎病毒的污染程度都不高。

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