Asmal A C, Leary W P
Postgrad Med J. 1975;51 Suppl 1(593):144-8.
Assessment of the significance of the presence or absence of pathogenic bacteria in sputum specimens is made difficult by a number of factors which are discussed. It is now generally accepted that is the organism most commonly responsible for recurrent or persistent sputum purulence in chronic lower respiratory disease. The close association between this organism and chronic bronchitis has been confirmed by studies of precipitin antibodies. In patients with cystic fibrosis precipitin antibodies to and are frequently present: they are less commonly found in patients with bronchiectasis and very rarely in patients with chronic bronchitis.
多种因素使得评估痰标本中病原菌的存在与否的意义变得困难，这些因素将在文中进行讨论。目前普遍认为，[此处原文缺失具体病菌名称]是慢性下呼吸道疾病中反复或持续痰液脓性化最常见的病原体。通过沉淀素抗体研究已证实该病原体与慢性支气管炎之间存在密切关联。在囊性纤维化患者中，针对[此处原文缺失具体病菌名称]和[此处原文缺失具体病菌名称]的沉淀素抗体经常出现：在支气管扩张症患者中较少见，而在慢性支气管炎患者中则非常罕见。
