Blancher A, Ruffié J, Socha W W
Centre Régional de Transfusion Sanguine, CHU Purpan, Toulouse, France.
J Med Primatol. 1993 Jan;22(1):13-8.
Six chimpanzee alloimmune antibodies define 20 phenotypes of the R-C-E-F blood group system, the counterpart of the human Rh system. Of the several specificities of this system, the Rc constitutes the crucial link with human Rh since the reactions of some chimpanzee alloimmune anti-Rc sera with human red cells parallel those obtained with human anti-Rho reagents. Reciprocally, properly absorbed human anti-Rho sera detect Rc specificity on chimpanzee red cells. Tests with large panels of human monoclonal anti-D antibodies confirm the notion of shared epitopes between human alloantigen Rho(D) and chimpanzee alloantigen Rc.
六种黑猩猩同种免疫抗体定义了R - C - E - F血型系统的20种表型，该系统相当于人类的Rh系统。在这个系统的几种特异性中，Rc构成了与人类Rh的关键联系，因为一些黑猩猩同种免疫抗Rc血清与人类红细胞的反应与人抗Rho试剂所获得的反应相似。相应地，经过适当吸收的人抗Rho血清可检测黑猩猩红细胞上的Rc特异性。用大量人类单克隆抗D抗体进行的测试证实了人类同种抗原Rho(D)和黑猩猩同种抗原Rc之间存在共同表位的观点。
