Tugume S B, Piwowar E M, Lutalo T, Mugyenyi P N, Grant R M, Mangeni F W, Pattishall K, Katongole-Mbidde E
Joint Clinical Research Centre, Makerere University Medical School, Kampala, Uganda.
Clin Diagn Lab Immunol. 1995 Mar;2(2):233-5. doi: 10.1128/cdli.2.2.233-235.1995.
Reference values are essential for the interpretation of hematologic data in clinical practice and research studies. Symptom-free human immunodeficiency virus antibody-negative Ugandan adults (183 subjects, aged 15 to 74 years, 37.7% women and 62.3% men) were studied to establish hematological reference ranges. The central 95% areas under the distribution curves were 1,453 to 4,448 cells per microliters for the absolute lymphocyte count, 559 to 2,333 cells per microliters for the absolute CD4 count, 253 to 1,396 cells per microliters for the absolute CD8 count, and 0.68 to 4.4 for the CD4/CD8 ratio. Women had significantly higher mean absolute lymphocyte counts (2,826 versus 2,568/microliters), absolute CD4 counts (1,425 versus 1,154/microliters) and absolute CD4/CD8 ratios (2.58 versus 1.88) than did men. These reference ranges differ from those reported for populations outside Africa.
参考值对于临床实践和研究中血液学数据的解读至关重要。对无症状的人类免疫缺陷病毒抗体阴性的乌干达成年人（183名受试者，年龄15至74岁，女性占37.7%，男性占62.3%）进行了研究，以确定血液学参考范围。分布曲线下中央95%区域的绝对淋巴细胞计数为每微升1453至4448个细胞，绝对CD4计数为每微升559至2333个细胞，绝对CD8计数为每微升253至1396个细胞，CD4/CD8比值为0.68至4.4。女性的平均绝对淋巴细胞计数（2826对2568/微升）、绝对CD4计数（1425对1154/微升）和绝对CD4/CD8比值（2.58对1.88）显著高于男性。这些参考范围与非洲以外人群报告的参考范围不同。
