van den Berg R, Peters J A, van Bekkum H
Laboratory of Organic Chemistry and Catalysis, Delft University of Technology, Netherlands.
Carbohydr Res. 1995 Feb 1;267(1):65-77. doi: 10.1016/0008-6215(94)00282-k.
Lactose, maltose, cellobiose, and galactose can be degraded selectively in one step and in high yield into the corresponding next lower aldose and formic acid by H2O2 in the presence of borate. The selectivity further improves when a small amount of EDTA is added, in order to suppress the influence of transition metal ions which catalyze the decomposition of H2O2 via radical pathways, leading to non-selective oxidative degradation of aldoses. The function of borate in the selective oxidative degradation of aldoses is two-fold: catalysis of the degradation of the starting aldose and protection of the next lower aldose against oxidation.
乳糖、麦芽糖、纤维二糖和半乳糖在硼酸盐存在下，可通过过氧化氢一步选择性降解，并高产率地转化为相应的下一个低级醛糖和甲酸。当添加少量乙二胺四乙酸（EDTA）时，选择性进一步提高，以抑制过渡金属离子的影响，过渡金属离子通过自由基途径催化过氧化氢分解，导致醛糖发生非选择性氧化降解。硼酸盐在醛糖选择性氧化降解中的作用有两个方面：催化起始醛糖的降解以及保护下一个低级醛糖不被氧化。
