14号染色体的CEPH联合体图谱。

CEPH consortium map of chromosome 14.

作者信息

Cox D W, Billingsley G D, Bale A E, Donis-Keller H, Edwards J H, Litt M, Mcbride W, Persichetti F, Spurr N K, Weber J L

机构信息

Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

Cytogenet Cell Genet. 1995;69(3-4):175-8. doi: 10.1159/000133955.

DOI:10.1159/000133955

PMID:7698005

Abstract

Families from the linkage panel of Centre d'Etude du Polymorphisme Humain have been used to generate a linkage map containing 68 loci; 13 genes, 33 di- and 4 tetranucleotide repeats, one oligonucleotide ligation assay (OLA), and 17 RFLPs. This map integrates markers from several previous maps, and has undergone further error checking. 43 loci have been placed with odds of 1000:1 or greater, five with odds of 100:1, with an average interval of 3.5 cM. An additional 20 loci have been placed within defined intervals.

摘要

来自人类多态性研究中心连锁小组的家族已被用于构建一个包含68个位点的连锁图谱；其中有13个基因、33个二核苷酸和4个四核苷酸重复序列、1个寡核苷酸连接分析（OLA）以及17个限制性片段长度多态性（RFLP）。该图谱整合了先前几个图谱中的标记，并经过了进一步的错误检查。43个位点的定位概率为1000:1或更高，5个位点的定位概率为100:1，平均间隔为3.5厘摩。另外20个位点已被定位在特定区间内。