Nicholson A M, Glynn A A
Br J Exp Pathol. 1975 Dec;56(6):549-53.
Urinary infection could be produced in mice by the inoculation of Escherichia coli into the bladder, provided that sutures had first been inserted into the bladder wall to act as foreign bodies. While the bladder was almost always infected, thekidneys were involved less often. The frequency of kidney infection was directly proportional to the K antigen of the infecting strain of E. coli. The significance of K antigens in relation to host defence mechanisms and tissue invasion is discussed.
如果事先将缝线插入膀胱壁作为异物，那么通过向膀胱接种大肠杆菌可在小鼠中引发尿路感染。虽然膀胱几乎总是受到感染，但肾脏受感染的情况较少见。肾脏感染的频率与感染性大肠杆菌菌株的K抗原直接相关。本文讨论了K抗原与宿主防御机制及组织侵袭的关系。
