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内镜下括约肌切开术后胆总管结石残留:胆道支架置入的短期和长期治疗

Retained common bile duct stones after endoscopic sphincterotomy: temporary and longterm treatment with biliary stenting.

作者信息

Maxton D G, Tweedle D E, Martin D F

机构信息

South Manchester University Hospital.

出版信息

Gut. 1995 Mar;36(3):446-9. doi: 10.1136/gut.36.3.446.

Abstract

Basket extraction after endoscopic sphincterotomy failed to clear the bile ducts immediately in 85 (30%) of 283 consecutive patients with common bile duct stones. Temporary biliary drainage was established by the insertion of a single 7 Fr double pigtail stent before further planned endoscopic attempts at stone removal. In 84 patients (21 male: 63 female, mean age 77 years) this measure relieved biliary obstruction, mean serum bilirubin falling from 101 to 18 umol/l by the time of the second endoscopic retrograde cholangiopancreatography. Six patients died from non-biliary causes with temporary stents in situ. Common bile duct stone extraction was achieved endoscopically in 50 of the remaining 79 patients after a mean of 4.3 months (range 1-12), 34 (68%) requiring only one further procedure. Three patients were referred for biliary surgery. Single stents were also effective for longterm biliary drainage in the remaining 26 elderly patients with unextractable stones. The main biliary complication of stenting was 13 episodes of cholangitis but all except one responded to medical treatment and early stent exchange. If common bile duct stones remain after endoscopic sphincterotomy, a single 7 Fr double pigtail stent is effective and safe for temporary biliary drainage before further endoscopic attempts at duct clearance and for longterm biliary drainage especially in the old and frail.

摘要

在283例连续性胆总管结石患者中,85例(30%)在内镜下括约肌切开术后行篮式取石未能立即清除胆管结石。在进一步计划内镜取石之前,通过插入一根7F双猪尾支架建立临时胆道引流。在84例患者(21例男性,63例女性,平均年龄77岁)中,这一措施缓解了胆道梗阻,到第二次内镜逆行胰胆管造影时,血清胆红素均值从101 μmol/L降至18 μmol/L。6例患者带临时支架在位时死于非胆道原因。其余79例患者中,平均4.3个月(1 - 12个月)后,50例通过内镜成功取出胆总管结石,34例(68%)仅需再进行一次操作。3例患者被转诊接受胆道手术。单根支架对其余26例无法取出结石的老年患者进行长期胆道引流也有效。支架置入的主要胆道并发症是13次胆管炎发作,但除1例之外均对药物治疗和早期更换支架有反应。如果内镜下括约肌切开术后仍残留胆总管结石,一根7F双猪尾支架对于进一步内镜清除胆管结石之前的临时胆道引流以及尤其是对老年体弱患者的长期胆道引流是有效且安全

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