Calin A, Garrett S, Whitelock H, Kennedy L G, O'Hea J, Mallorie P, Jenkinson T
Royal National Hospital for Rheumatic Diseases, Bath, UK.
J Rheumatol. 1994 Dec;21(12):2281-5.
After pain and stiffness, one of the most important complaints of patients with ankylosing spondylitis (AS) is disability. The main aims of treatment are to control pain but also to improve function. Various methods of assessing function exist but are either not specific for the disease or have not been adequately validated. As a result of this deficiency we developed the Bath Ankylosing Spondylitis Functional Index (BASFI) as a new approach to defining and monitoring functional ability in patients with AS.
This self-assessment instrument was designed by a team of medical professionals in conjunction with patients, and consists of 8 specific questions regarding function in AS and 2 questions reflecting the patient's ability to cope with everyday life. Each question is answered on a 10 cm horizontal visual analog scale, the mean of which gives the BASFI score (0-10). The questionnaire was completed 257 times in total: once by 116 outpatients and by 47 inpatients on 3 occasions over a 3-week intensive physiotherapy course. In addition, the instrument was compared with the Dougados functional index.
Patients scores covered 95% of the BASFI range, giving a normal distribution of results. In contrast only 65% of the Dougados functional index scale was used. Furthermore, over the 3 week period of inpatient treatment, the BASFI revealed a significant improvement in function (20%, p = 0.004) while there was a less impressive change in the Dougados functional index (6%, p = 0.03). This demonstrates the superior sensitivity of the BASFI: Consistency was good for both indices (p < 0.001), as was the relationship between patient perception of function and function as assessed by an external observer (p < 0.001).
The BASFI satisfies the criteria required of a functional index: it is quick and easy to complete, is reliable and is sensitive to change across the whole spectrum of disease.
除疼痛和僵硬外,强直性脊柱炎(AS)患者最重要的主诉之一是残疾。治疗的主要目标是控制疼痛,同时改善功能。存在多种评估功能的方法,但要么对该疾病不具特异性,要么未得到充分验证。由于这一缺陷,我们开发了巴斯强直性脊柱炎功能指数(BASFI),作为定义和监测AS患者功能能力的一种新方法。
这种自我评估工具由一组医学专业人员与患者共同设计,包括8个关于AS功能的具体问题以及2个反映患者日常生活应对能力的问题。每个问题通过10厘米的水平视觉模拟量表进行回答,其平均值即为BASFI评分(0 - 10分)。该问卷总共完成了257次:116名门诊患者各完成一次,47名住院患者在为期3周的强化物理治疗课程中分3次完成。此外,该工具还与杜加多斯功能指数进行了比较。
患者评分覆盖了BASFI范围的95%,结果呈正态分布。相比之下,杜加多斯功能指数量表仅使用了65%。此外,在住院治疗的3周期间,BASFI显示功能有显著改善(20%,p = 0.004),而杜加多斯功能指数的变化则不太明显(6%,p = 0.03)。这证明了BASFI具有更高的敏感性:两个指数的一致性都很好(p < 0.001),患者对功能的感知与外部观察者评估的功能之间的关系也是如此(p < 0.001)。
BASFI符合功能指数所需的标准:完成快速简便,可靠且对疾病全谱变化敏感。