Garrett S, Jenkinson T, Kennedy L G, Whitelock H, Gaisford P, Calin A
Royal National Hospital for Rheumatic Diseases, Bath, UK.
J Rheumatol. 1994 Dec;21(12):2286-91.
Disease status, in terms of disease activity, disease progression and prognosis is difficult to define in ankylosing spondylitis (AS). No gold standard exists. Therefore, the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), a self-administered instrument, has been developed as a new approach to defining disease activity in patients with AS.
The index, designed by a multidisciplinary team with input from patients, consists of six 10 cm horizontal visual analog scales to measure severity of fatigue, spinal and peripheral joint pain, localized tenderness and morning stiffness (both qualitative and quantitative). The final BASDAI score has a range of 0 to 10. The index was distributed to a cross section of patients, including inpatients receiving 3 weeks of intensive physiotherapy treatment and hospital outpatients. BASDAI was completed by a total of 154 patients. Validation of the new instrument was achieved through analysis of user friendliness, reliability (consistency), score distribution and sensitivity to change. Comparisons were made with a previous Bath disease activity index (DAI) and the Newcastle Enthesis Index.
The BASDAI was found by patients to be quick and simple to complete (mean: 67 s). Test-retest reliability was good (r = 0.93; p < 0.001), as was the distribution of scores across the scale (score range: 0.5-10; mean: 4.31). BASDAI was sensitive to change, reflecting a 16% (mean) improvement in inpatient scores after 3 weeks of treatment. It is superior to the DAI in terms of construct and content validity and to the Enthesis Index in all aspects.
In summary, BASDAI is user friendly, reliability, sensitive to change and reflects the entire spectrum of disease. It is a comprehensive self-administered instrument for assessing disease activity in AS.
强直性脊柱炎（AS）的疾病状态，包括疾病活动度、疾病进展和预后，很难进行界定。不存在金标准。因此，巴斯强直性脊柱炎疾病活动指数（BASDAI）这一自行填写的工具被开发出来，作为界定AS患者疾病活动度的一种新方法。
该指数由一个多学科团队在患者参与下设计而成，包含六个10厘米长的水平视觉模拟量表，用于测量疲劳、脊柱和外周关节疼痛、局部压痛以及晨僵（包括定性和定量）的严重程度。最终的BASDAI评分范围为0至10分。该指数分发给了各类患者，包括接受为期3周强化物理治疗的住院患者和门诊患者。共有154名患者完成了BASDAI。通过分析其易用性、可靠性（一致性）、评分分布以及对变化的敏感性，对这一新工具进行了验证。与先前的巴斯疾病活动指数（DAI）和纽卡斯尔附着点指数进行了比较。
患者认为BASDAI填写起来快速简便（平均用时：67秒）。重测信度良好（r = 0.93；p < 0.001），评分在量表上的分布情况也良好（评分范围：0.5 - 10；平均：4.31）。BASDAI对变化敏感，反映出住院患者在治疗3周后评分平均提高了16%。在结构效度和内容效度方面，它优于DAI，在各方面均优于附着点指数。
总之，BASDAI易用、可靠、对变化敏感且能反映疾病的全貌。它是一种用于评估AS疾病活动度的综合性自行填写工具。
