Benzerara N, Combemale P, Abitan R, Kanitakis J, Guennoc B, Chouvet B
Hôpital d'Instruction des Armées Desgenettes, Lyon.
Ann Dermatol Venereol. 1994;121(6-7):489-92.
Xanthogranuloma (XG) is a rare disease in adults. The authors report a case of XG in an 20 years-old woman. This observation is particularly interesting: First by the pathology of the cutaneous lesion which showed a dermal infiltrate composed of histiocytes and a few foamy cells but without Touton giant cells. Second by is association with a mastocytosis which disappeared when XG appeared. These data led the authors to discuss the misleading histology pattern of XG and also the pathogenesis of XG. In our case, it would appeared as a benign reactive process against mastocytosis.
黄色肉芽肿(XG)在成人中是一种罕见疾病。作者报告了一例20岁女性的黄色肉芽肿病例。该病例特别有趣:首先是皮肤病变的病理表现,显示真皮浸润由组织细胞和少数泡沫细胞组成,但无杜顿巨细胞。其次是它与肥大细胞增多症相关,当黄色肉芽肿出现时肥大细胞增多症消失。这些数据促使作者讨论黄色肉芽肿具有误导性的组织学模式以及黄色肉芽肿的发病机制。在我们的病例中,它似乎是针对肥大细胞增多症的一种良性反应过程。