Marty-Ané C H, SerreCousiné O, Laborde J C, Costes V, Mary H, Senac J P
Department of Thoracic and Vascular Surgery, Hôpital Arnaud de Villeneuve, Centre Hôspitalier Universitaire, Montpellier, France.
J Vasc Interv Radiol. 1995 Jan-Feb;6(1):97-103. doi: 10.1016/s1051-0443(95)71069-7.
To evaluate obliteration of an experimental aortic dissection with a balloon-expandable intravascular stent.
Fourteen adult dogs were divided into two groups. In group 1 (n = 6), a thoracoabdominal aortic dissection was surgically created to observe the natural course of this lesion. In group 2 (n = 8), a balloon-expandable intraluminal vascular graft was introduced via the femoral artery in a dissected aorta to try to obliterate the dissection. Angiography was performed postoperatively and again 6 weeks later before the aortae were explanted for pathologic evaluation.
In group 1, postoperative aortography depicted evidence of aortic dissection in all animals. Autopsy revealed persisting dissection with reentry tear near the celiac axis in five animals. In group 2, placement of a stent at only entry and reentry sites resulted in partial obliteration of the dissection (n = 3). When the entire length of dissected aorta was treated, the dissection was completely obliterated (n = 4).
An aortic dissection can be obliterated with a balloon-expandable stent if the entire dissected aorta is treated.
评估使用球囊扩张型血管内支架闭塞实验性主动脉夹层。
14只成年犬分为两组。第1组（n = 6），通过手术制造胸腹主动脉夹层以观察该病变的自然病程。第2组（n = 8），经股动脉将球囊扩张型腔内血管移植物置入已形成夹层的主动脉内，试图闭塞夹层。术后及6周后在取出主动脉进行病理评估前再次进行血管造影。
第1组，术后主动脉造影显示所有动物均有主动脉夹层的证据。尸检发现5只动物的夹层持续存在，在腹腔干轴附近有再入口撕裂。第2组，仅在入口和再入口部位放置支架导致夹层部分闭塞（n = 3）。当治疗整个夹层主动脉长度时，夹层完全闭塞（n = 4）。
如果治疗整个夹层主动脉，球囊扩张型支架可闭塞主动脉夹层。
