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用于实验性主动脉夹层的可扩张主动脉内假体的研发。

Development of an expandable intra-aortic prosthesis for experimental aortic dissection.

作者信息

Kato M, Ohnishi K, Kaneko M, Imagawa H, Ueda T, Kuratani T, Yoshioka Y, Matsuda T

机构信息

Division of Cardiovascular Surgery, Osaka Prefectural Hospital, Japan.

出版信息

ASAIO J. 1993 Jul-Sep;39(3):M758-61.

PMID:8268640
Abstract

To achieve transcatheter entry obliteration for Stanford type B dissection, the authors devised and developed a self-expandable intra-aortic prosthesis (IA graft). This graft consisted of a microporous polyurethane graft (wall thickness: 0.2 mm; average pore size: 0.1 mm) and an expandable metallic stent (Gianturco double stent) attached to the lumen surface of the polyurethane graft. Experimental dissections in the descending aorta of mongrel dogs were prepared. An IA graft was inserted through a femoral artery by a catheter sheath into which a compressed IA graft was installed and expanded at the entry site. After 30 min of graft implantation, closure of all the entry sites in four dogs was confirmed by aortography. The results suggest that the newly devised IA graft is extremely useful as a non invasive treatment for Stanford type B dissection.

摘要

为实现经导管封堵斯坦福B型主动脉夹层的入口,作者设计并开发了一种可自膨胀的主动脉内假体(IA移植物)。该移植物由微孔聚氨酯移植物(壁厚:0.2毫米;平均孔径:0.1毫米)和附着在聚氨酯移植物管腔表面的可膨胀金属支架(Gianturco双支架)组成。在杂种犬的降主动脉中制备实验性夹层。通过导管鞘将IA移植物经股动脉插入,压缩的IA移植物安装在导管鞘中并在入口部位展开。移植物植入30分钟后,通过主动脉造影证实四只犬的所有入口部位均已封闭。结果表明,新设计的IA移植物作为斯坦福B型主动脉夹层的非侵入性治疗方法极为有用。

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Development of an expandable intra-aortic prosthesis for experimental aortic dissection.用于实验性主动脉夹层的可扩张主动脉内假体的研发。
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Development of a chronic endothelialized transcatheter implantable intra-aortic graft.一种慢性内皮化经导管植入式主动脉内移植物的研发。
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