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血卟啉和硫酸原黄素与都柏林沙门氏菌细胞的暗相互作用。

Dark interaction of haematoporphyrin and proflavine with Salmonella dublin cells.

作者信息

Veljanov D, Kussovski V, Radoucheva T, Najdenski H, Ilieva L, Cherepova N, Voivodov K, Genov N

机构信息

Institute of Microbiology, Bulgarian Academy of Sciences, Sofia.

出版信息

Cytobios. 1994;79(319):253-9.

PMID:7705104
Abstract

The influence of haematoporphyrin and proflavine on the virulence, survivability, respiratory activity and cell wall ultrastructure of Salmonella dublin cells was studied. There was a decrease in all biological properties investigated, especially when haematoporphyrin was used for dark incubation in comparison with proflavine. The possible clinical use of negatively charged photosensitizers is discussed.

摘要

研究了血卟啉和硫酸原黄素对都柏林沙门氏菌细胞的毒力、生存能力、呼吸活性和细胞壁超微结构的影响。所有研究的生物学特性均有所下降,特别是与硫酸原黄素相比,当用血卟啉进行暗培养时。讨论了带负电荷的光敏剂可能的临床应用。

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