Blohmer J U, Chaoui R, Schmalisch G, Bollmann R, Lau H U
Universitätsklinikum Charité, Medizinische Fakultät, Humboldt- Universität zu Berlin.
Geburtshilfe Frauenheilkd. 1995 Jan;55(1):1-6. doi: 10.1055/s-2007-1022765.
74 breast tumor patients were preoperatively examined by means of colour and pulsed-wave Doppler sonography using the ultrasonic instrument ALT Ultramark 9 HDI with a broad-band linear scanner, 5-10 MHz. The Doppler flow velocity waveforms, from the vessels of the mammary lesion (affected breast) and the corresponding quadrant of the contralateral breast (non-affected breast), respectively, were compared in respect of the four parameters maximal systolic velocity, minimal diastolic velocity, pulsatility index (PI) and resistance index (RI). In 48 cases we succeeded in representing arterial vessels both inside the affected and the contralateral breast. The aim of the study was to examine whether these parameters show a significantly different degree of deviation in correlation with the tumours being either benign or malign. In cases with benign lesions (n = 24) we did not find any significant differences in all the parameters that we examined. In cases with cancer, however (n = 18), a significantly higher systolic velocity was found in the affected breast compared to the contralateral breast, but there were no differences in the other parameters. Although the quantitative Doppler measurements are angle-dependent parameters, the study showed that the maximal velocity in the affected breast compared to the contralateral breast is the most useful parameter in differential diagnosis of breast tumours.
74例乳腺肿瘤患者术前使用配备5-10MHz宽带线性扫描器的ALT Ultramark 9 HDI超声仪，通过彩色和脉冲波多普勒超声进行检查。分别比较了乳腺病变（患侧乳房）和对侧乳房相应象限（未患侧乳房）血管的多普勒流速波形的四个参数：最大收缩速度、最小舒张速度、搏动指数（PI）和阻力指数（RI）。在48例患者中，成功显示了患侧乳房和对侧乳房内的动脉血管。本研究的目的是检查这些参数在与肿瘤为良性或恶性相关时是否显示出显著不同程度的偏差。在良性病变患者（n = 24）中，我们检查的所有参数均未发现任何显著差异。然而，在癌症患者（n = 18）中，发现患侧乳房的收缩速度明显高于对侧乳房，但其他参数没有差异。尽管定量多普勒测量是角度相关参数，但研究表明，患侧乳房与对侧乳房相比的最大速度是乳腺肿瘤鉴别诊断中最有用的参数。
